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PATIENT INFORMATION BOOKLETS

CLINICAL MANIFESTATIONS OF ALLERGY
HAIR

TYPES OF ALLERGY

Exogenic allergy is caused by various external allergens like industrial wastes, chemicals, insecticides, pesticides etc. Eventually, all allergens seem to cause gradual changes in the genetic make up and subsequently the allergy becomes Endogenic. The body tissues get 'sensitized' to various allergens and this leads to hypersensitivity reactions. These 'sensitized' response characteristics are passed on to the succeeding generations.

The fundamental cause of all allergies, therefore, is endogenic and in most cases it runs in the family tree of the patient.


Often allergy remains dormant in the patient's body system until a situation arises when the patient's immune system is at low guard and his resistance is highly compromised. 'Physical stress states' such as surgery, infections, serious diseases, pregnancy, old age etc. are some of the conditions because of which body gets predisposed to attacks by allergens.

Some of the commonest allergic diseases alternate in a patient's life. A patient suffering from eczema in childhood may suffer from Bronchial Asthma in adult hood. Usually there would be a history of Hay fever, Urticaria, Eczema, Asthma, Arthritis etc. in the family. Similarly hair problems, an allergic manifestation of skin, also have a genetic base and present with an inflammatory response as elucidated below.

Core Pathology in Hair loss -Inflammation: After puberty, Testosterone typically increases in the overall blood supply of most males. When DHT (Dihydrotesterone) and the Androgen receptors are in normal abundance, binding at normal rates, hair growth regulation is also normal. Hair grows and falls, as it should. The overabundance however, throws the whole process off the track.

The process described above initiates what is called an autoimmune response. Follicles experiencing this are suddenly considered foreign objects in the body, and the degradation is a direct result of the body rejecting them from the system. This is really what Male Pattern Baldness is all about.

One of the biggest signs of the autoimmune response is tingling, itching, redness, and inflammation of the scalp. Not all men losing hair experience this, but a vast majority does. Inflammation is considered one of the other major factors, which exacerbate the hair loss process. This further consolidates the concept of Allergy.

 

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